Sermorelin Reconstitution Calculator

Enter your vial size, bacteriostatic water, and dose to get your exact draw in insulin syringe units.

Reconstitution calculator

Enter your peptide amount, diluent volume, and target dose to see your draw.

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Units
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Target Dose
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Syringe Fill
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Doses per compound

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Draw 0.08 ml (8.3 units on a U-100 insulin syringe) for a 250 mcg dose.

You've got the math. Now the hard part is the schedule.

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Mixing Sermorelin: What to Know Before You Reconstitute

Sermorelin is a growth hormone releasing hormone analog supplied as a lyophilized powder, commonly in 5 mg, 9 mg, and 15 mg vials. Many people encounter it through a compounding pharmacy rather than as a research vial, which changes the starting point: pharmacy vials often arrive with a supplied diluent, a stated concentration, and instructions, in which case the reconstitution decision has already been made. The math below applies when you are mixing it yourself, and the calculator above is equally useful for checking a draw against a concentration someone else set.

  1. Bacteriostatic water vs. sterile water

    Bacteriostatic water contains 0.9% benzyl alcohol as a preservative, which is what allows a vial to be punctured repeatedly over days or weeks. Sterile water has no preservative and is generally treated as single use. Sermorelin is typically dosed frequently, so the vial sees many punctures, and bacteriostatic water is the conventional choice when a diluent was not supplied. If your pharmacy provided a diluent, use what they provided.

  2. How much water to add

    Water volume sets concentration, not content. A 9 mg vial contains 9 mg whether you add 2 mL or 3 mL. Sermorelin doses are usually discussed in micrograms, so the draws are small and the water volume mostly determines how readable those draws are on the syringe.

    VialWaterConcentrationPer unit200 mcg draw300 mcg draw
    5 mg2 mL2.5 mg/mL25 mcg8 units12 units
    9 mg3 mL3.0 mg/mL30 mcg6.7 units10 units
    9 mg4.5 mL2.0 mg/mL20 mcg10 units15 units
    15 mg5 mL3.0 mg/mL30 mcg6.7 units10 units

    The 9 mg vial in 4.5 mL is worth noting: it produces exactly 20 mcg per unit, so every 100 mcg is 5 units and the mental math disappears. Several conventional volumes are chosen for that kind of round number rather than for anything specific to the compound. Where a draw lands on a fraction of a unit, as 6.7 does above, the calculator will show the nearest marked lines on your syringe.

  3. Mixing technique

    Direct the liquid down the inside wall of the vial rather than onto the powder, then swirl gently or let it stand until fully dissolved. Do not shake. The finished solution should be clear with no visible particles.

  4. Storage before and after mixing

    Unopened vials keep cool and dark. Reconstituted vials are refrigerated. Where a pharmacy supplied the vial and diluent, the beyond use date they printed governs, and it is often shorter than the general convention. Where you mixed it yourself with bacteriostatic water, the usual roughly 28 day window applies. Either way the useful habit is recording the date the vial was mixed, since a frequently dosed vial can outlast or fall short of expectations depending on the concentration chosen.

  5. The syringe

    U-100 insulin syringes, where 100 units equal 1 mL. Because microgram doses produce small draws, the 0.3 mL and 0.5 mL syringes are often preferred over the 1 mL, since their markings sit further apart and small draws are easier to read accurately.

  6. Common mistakes worth avoiding

    The recurring ones: re-reconstituting a pharmacy vial that was already prepared, ignoring a printed beyond use date in favor of the general 28 day convention, using so little water that doses land on 3 or 4 units, mixing up mcg and mg during conversion, and carrying an old unit count over to a new vial mixed at a different volume.

FAQ

How much bacteriostatic water do I mix with a 9 mg sermorelin vial?
Common volumes run about 3 mL to 4.5 mL. At 9 mg in 4.5 mL the concentration is 2 mg/mL, or 20 mcg per unit, which makes a 200 mcg draw exactly 10 units. Water volume changes only the concentration, so pick one that gives a readable draw.
My sermorelin came from a pharmacy already mixed. Do I still need this?
The reconstitution step is already done, so the water volume decision is not yours to make. The calculator is still useful for converting your dose into syringe units at the concentration the pharmacy set, which is usually printed on the label.
How long does reconstituted sermorelin last in the fridge?
If a pharmacy prepared it, the beyond use date they printed governs and is often shorter than the general convention. If you mixed it yourself with bacteriostatic water, about 28 days refrigerated is the usual window.
Why are my sermorelin draws so small?
Microgram doses at typical concentrations produce draws of only a few units. Adding more bacteriostatic water lowers the concentration and spreads the same dose across more units, which is easier to measure.
What size syringe do people use for sermorelin?
Frequently a 0.3 mL or 0.5 mL U-100 insulin syringe, because the wider spacing between markings makes small draws easier to read than on a 1 mL syringe.

PepKit's calculator is an arithmetic tool for reconstitution math. It does not provide dosing recommendations or medical advice. Follow the guidance of your provider or protocol.